Preimplantation genetic diagnosis (PGD) screens for specific genetic diseases
Preimplantation genetic diagnosis (PGD) refers to the testing of embryos for a specific genetic disease, such as cystic fibrosis or sickle cell anemia.
Preimplantation genetic screening (PGS) tests for the number of chromosomes
Preimplantation genetic screening tests embryos to ensure they have a normal number of chromosomes. This allows us to identify anomalies such as trisomy 21 (Down syndrome) or trisomy 16 (a common cause of miscarriage) prior to embryo transfer.
Preimplantation genetic diagnosis (PGD) can greatly reduce the risk of certain diseases
Parents who are both genetic carriers of an autosomal recessive condition (like cystic fibrosis) have a 1 in 4 chance of having an affected child. By identifying affected embryos prior to transfer, parents can greatly reduce the chance of having a child with a particular genetic condition. Preimplantation genetic diagnosis is widely used for conditions such as cystic fibrosis, sickle cell anemia, and Tay Sachs. It can also be customized for even the rarest genetic conditions.
Preimplantation genetic screening (PGS) can reduce the risk of miscarriage
Preimplantation genetic screening can be performed to screen the embryos for chromosomal abnormalities incompatible with life such as trisomy 16 and 18 and other conditions associated with miscarriage. Additionally, it can screen for trisomy 21 (Down syndrome). By selecting the embryo with normal chromosomes, parents can reduce the chance of having a miscarriage due to chromosomal abnormalities.
Testing is performed before embryos are implanted
If you choose either preimplantation genetic diagnosis, preimplantation genetic screening, or both, you will undergo a stimulated IVF cycle.
Multiple eggs are retrieved and fertilized. Then the embryologist takes a biopsy of your embryo which is sent for analysis. Because the results will take several days to obtain, the embryo is then cryopreserved (frozen). The next month, after reviewing the results, you will undergo a frozen embryo transfer cycle.
We know how anxious you’ll be for the results, so we now offer a 24 hour turnaround time with 24 chromosome panel.
We partner with the Genetics Institute, ReproGenetics, and Good Start Genetics
Dominion Fertility is proud to partner with the Genetics Institute, a national leader in the field of preimplantation genetic diagnosis. We also partner with ReproGenetics and Good Start Genetics, well established and reliable genetic laboratories. We chose these partners to help us give our patients the best best genetic analysis and clinical outcomes available in the country.
Success rates are similar to those of our regular IVF programs
Learn more about our IVF success rates.