I Had an Allergic Reaction to the Progesterone In Oil Shots. Does This Mean That I Cannot Do IVF?

I Had an Allergic Reaction to the Progesterone In Oil Shots. Does This Mean That I Cannot Do IVF?

October 26, 2011
#
min read
Woman using progesterone-in-oil injections

Following follicle aspiration, most clinics place patients on progesterone supplementation. The rationale behind the supplemental progesterone is that following egg collection, ovarian hormone production may be impaired because many of the hormone-producing cells are removed at the time of follicle aspiration. In addition, the use of GnRH agonists such as Lupron may diminish ovarian steroid production following egg collection. Progesterone supplementation has evolved over the years to include patients undergoing both stimulated IUI cycles and IVF.

Although many clinics tend to use progesterone-in-oil injections, equivalent pregnancy rates have been reported in patients using only vaginal progesterone supplementation. Allergic reactions to progesterone are infrequent, but switching patients to vaginal progesterone usually resolves the problem.

Another strategy to maintain progesterone production after IUI or egg collection involves the use of HCG booster shots to enhance steroid production from the patient’s ovaries rather than relying on an outside source. Unfortunately, the use of HCG boosters may also increase the woman’s risk of ovarian hyperstimulation syndrome.

Related Blogs

41 Year Old Successful Pregnancy with IVF and PGS
June 29, 2016
Events & Announcements

41 Year Old Successful Pregnancy with IVF and PGS

Read More
What Is Endometriosis and How Is It Diagnosed?
September 27, 2018
Infertility Resources & Support

What Is Endometriosis and How Is It Diagnosed?

Read More
Fact or Fiction? Investigating 7 Common Fertility & Pregnancy Myths
December 19, 2019
Preconception Health

Fact or Fiction? Investigating 7 Common Fertility & Pregnancy Myths

Read More